FILE - In this Oct. 11, 1982 file photo, first lady Nancy Reagan speaks at the first national conference of the National Federation of Parents for Drug-Free Youth in Washington. “Many people think drug prevention is ‘just say no,’ like Nancy Reagan did in the '80s, and we know that did not work,” said Becky Vance, CEO of the Texas-based agency Drug Prevention Resources, which has advocated for evidenced-based anti-drug and alcohol abuse education for more than 85 years. (AP Photo/Barry Thumma, File)