FILE - In this Nov. 18, 1988 file photo, former President Ronald Reagan hands a pen to then first lady Nancy Reagan after he signed a major anti-drug bill at a White House East Room ceremony in Washington. Reagan dedicated the bill to Nancy, who has led a "Just Say No" campaign among America's youth, and gave her the pen he used to sign the bill with. Nancy Reagan, who died Sunday, March 6, 2016, is perhaps best known for her "Just Say No" to drugs and alcohol campaign. Three decades after the campaign's heyday, prevention experts credit it with spawning a new generation of research into the best ways of reducing drug abuse. But they also say that many of the fear-based tactics it embraced didn't work. (AP Photo/Ron Edmonds, File)